What We Do
In 2012, we launched the San Antonio 1000 Cancer Genome Project. This ambitious project will do what almost no one else can do. By joining forces with this city’s top cancer surgeons, we are collecting fresh tumor tissue of the 10 most common cancers in San Antonio from 1000 patients. We will then perform whole genome sequencing on the cancerous and normal tissue from each patient and will link this genetic information to the patient’s clinical course annotated in the state of the art electronic medical record at the START Center for Cancer Care, the largest oncology practice in San Antonio. By doing so, we will create the only prospective longitudinal study of the whole cancer genome and relate this to patient outcome. We will then make this database freely available to all researchers worldwide so that bright minds within and beyond our city borders can analyze the data and make the necessary breakthroughs in cancer medicine. This Open Science approach acknowledges that no single investigator or institution has all of the answers and encourages the involvement of outsiders who might bring fresh ideas to the urgent and complex problem of gene abnormalities and cancer. Due to the involvement of over 200 surgeons, oncologists, and cancer researchers from a broad spectrum of affiliations, this is the largest community-wide genome undertaking of its kind. This well-defined project steps beyond the institutional barriers that currently fragment and piecemeal cancer research, and may forever change the way we think about and treat cancer.
Aimee J. Locke, President
Attorney and Philanthropist
Gina L. Mangold, Secretary
Chief Operating Officer of South Texas Accelerated Research Therapeutics (START)
Lon S. Smith, Director
Medical Oncologist at The START Center